 LSM 710 ConfoCor 3 |
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 Biochemical processes determine the structures and functions of cells.
With the combination of a confocal laser scanning microscope and a fluorescence correlation spectrometer, structures can be made visible and, at the same time, be investigated biochemically. |
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| | Single Molecules in the (Laser) Focus
Versatile measurements in solutions and cells: concentrations, interactions, fluctuations, diffusions – that's the ConfoCor 3.
A solid basis.
The ConfoCor 3 is directly attached to the channel output of the LSM 710. This choice of attachment gives you highest flexibility for your required setup.
The combination provides 36 channels:
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| • | 2x PMT |
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| • | 1x Spectral detector with 32 channels |
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| • | 2x APD |
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You want to know how single molecules or defined molecule ensembles behave in your reaction tube or your cellular compartment? You want to learn about their dynamic behavior and their preferred interaction partners? The ConfoCor 3 will be an ideal choice. It measures precisely with highest sensitivity and quickly within seconds. Based on the confocal detection principle, the diffusion speed and concentration of a fluorescent labeled molecule is easily accessed in a single measurement by the correlation function.
No compromise in sensitivity.
The new C-Apochromat 40x / W 1.2 (UV-VIS-IR) high numerical aperture objective guarantees a maximum collection efficiency of photons emitted by an excited molecule. These photons are detected with highest sensitivity by avalanche photodiodes (APDs). Rely on efficient colour correction for best cross-correlation results.
Marriage of Optics and Mathematics.
The confocal volume is produced by focusing the laser beam on the physically smallest possible spot using high precision optics. Recorded fluctuations in fluorescence are then analyzed by a sophisticated mathematical equation, the correlation function.
Automation to enhance user comfort.
The ConfoCor 3 is fully motorized and computer controlled, enabling the automation of measurement protocols. High reproducibility in your measurements, high sample throughput and delegation of routine measurements go without saying.
Flexibility through data export.
The ConfoCor 3 gathers photons for you. And you can do whatever you want with them. The ConfoCor 3 memorizes the raw data, and you can evaluate them in your own ways.
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