ILEXIUM 2022

20 - 21 June 2022
Kameha Grand Bonn, Germany

Registration deadline
13 June 2022

Welcome to ILEXIUM

Live & in-person in Bonn

As the global COVID-19 pandemic hopefully calms down during the next couple of months and gradually allows for more freedom again, also long-desired live congresses with podium speeches, poster presentations and face-to-face meetings are slowly becoming reality again – also ILEXIUM!

Therefore, it is our greatest pleasure to invite you to the upcoming International Low Energy X-ray IORT User Meeting (ILEXIUM) which will take place on 20 - 21 June 2022 in the historical city of Bonn, Germany to address topics concerning intraoperative radiotherapy (IORT) and give the IORT community the possibility to finally meet and socialize face-to-face again. The event is officially hosted by ZEISS and takes place in consideration of the official COVID-19 regulations of the Federal Republic of Germany.

Elena Sperk, MD
University Medical Center Mannheim,
Germany

^{We are delighted to have you with us to participate in the first post-pandemic ILEXIUM in 2022. This conference has come a long way and yet it has surpassed the various challenges that our health systems have faced over the last two years. This year, it holds two special values: …}

Frank A. Giordano, MD
University Hospital Bonn,
Germany

Warm regards, Elena Sperk & Frank A. Giordano (Conference Chairs)
^{… First, it is held as an in-person event after a long period of dry and exhausting video sessions. Second, it is - for the first time - not taking place in Mannheim, but in Bonn, the city of Beethoven and former capital of the Federal Republic of Germany. Please enjoy the live meeting and the great program we have compiled.}

Scientific program

Exchange & Inspire

As always, the scientific program of ILEXIUM will provide a wealth of information about intraoperative radiotherapy, ongoing clinical trials and study results, as well as the latest advancements and further developments of IORT. In addition, it is a splendid opportunity to directly learn from your peers and get first-hand experiences about IORT in the clinical practice.

We would like to encourage you to be part of this exciting IORT community and actively contribute to the scientific program with oral presentations and poster sessions. As a special highlight we will sponsor one hotel night including breakfast per person for the first 30 submitted abstracts.

Take your chance, make this event unique & submit your abstract.

Scientific Program

The meeting starts with a warm welcome from the conference chairs, Frank A. Giordano and Elena Sperk, followed by the scientific program which is categorized in various topics and each category is chaired by leading international experts.

Monday, 20 June 2022

Start	End		Program	Chair & Speaker	Institution
1:00 PM	1:15 PM		Welcome Reception & Opening Remarks	Elena Sperk	University Medical Center Mannheim, Germany
1:00 PM	1:15 PM		Welcome Reception & Opening Remarks	Frank A. Giordano	University Hospital Bonn, Germany
1:15 PM	2:15 PM	Keynotes: Brain & Spine I		Henning Kahl	University Hospital Augsburg, Germany
1:15 PM	2:15 PM	Keynotes: Brain & Spine I		Udo Obertacke	University Medical Center Mannheim, Germany
		Challenges in tumor response assessment in neuro-oncology		Kevin Petrecca	McGill University Health Centre, Canada
		INTRAGO past, present & future		Frank A. Giordano	University Hospital Bonn, Germany
		Joint session with NOA: ongoing clinical trials from the German Neuro-Oncology Working Group		Stephanie Combs	University Medical Center Mannheim, Germany
		IORT for brain metastases: rationale & outcomes		Christopher P. Cifarelli	West Virginia University, USA
2:15 PM	2:45 PM		Break
2:45 PM	4:20 PM		Session: Breast Cancer	Ferran Guedea	Institut Catala d'Oncologia, Spain
2:45 PM	4:20 PM		Session: Breast Cancer	Elena Sperk	University Medical Center Mannheim, Germany
			Keynote: Breast preservation + IORT or mastectomy: long-term QoL outcomes	Hans-Christian Kolberg	Marienhospital Bottrop, Germany
			Institutional experience with IORT as APBI in early breast cancer	Evelyn Martínez Pérez	Catalan Institute of Oncology, Spain
			Breast-Q in patients with breast conserving treatment and low-energy intraoperative radiotherapy	Maria Jesus Pla Farnós	Hospital Universitari de Bellvitge, Spain
			Development and future of intraoperative radiotherapy based on single institution experiences	Zaneta Kaniszewska-Dorsz	Maria Sklodowska-Curie National Research Institute of Oncology, Poland
			Targeted intraoperative radiotherapy for early breast cancer: cosmetic advantages and acute toxicities - a single Institution’s experience	Slavyana Usheva	University Hospital Queen Joanna - ISUL, Bulgaria
			Long-term outcomes of an international cooperative study of intraoperative radiotherapy upfront boost with low energy X-rays in breast cancer	Gustavo R. Sarria	University Hospital Bonn, Germany
			Intraoperative radiotherapy in patients with implanted pacemakers based on single institution experience	Zaneta Kaniszewska-Dorsz	Maria Sklodowska-Curie National Research Institute of Oncology, Poland
			Comparison of dose distributions: planning, navigation and considering actual applicator position	César Frenando Vivo de Catarina	Universidad de Las Palmas de Gran Canaria, Spain
			Intraoperative radiotherapy experience at Clinica Leopoldo Aguerrevere, Caracas-Venezuela	Alecia Cosson	Clínica Leopoldo Aguerrevere, Venezuela
4:20 PM	4:50 PM		Coffee Break
4:50 PM	5:20 PM		Keynotes: Radiation Biology of IORT	Gustavo J. Sarria Bardales	AUNA Oncosalud Clinic, Peru
4:50 PM	5:20 PM		Keynotes: Radiation Biology of IORT	Gustavo R. Sarria	University Hospital Bonn, Germany
			Intraoperative tumor-bed irradiation and immune effects of high radiation doses	Carsten Herskind	University Medical Center Mannheim, Germany
			Modifications induced by radiation in tumor bed microenvironment	Pedro Lara	San Roque University Hospital, Spain
5:20 PM	5:30 PM		Closing Remarks	Elena Sperk	University Medical Center Mannheim, Germany
5:20 PM	5:30 PM		Closing Remarks	Frank A. Giordano	University Hospital Bonn, Germany
5:30 PM	6:30 PM		Break
6:30 PM	9:30 PM		The Emami Reception Lecture	Bahman Emami	Loyola University Medical Center, USA

Tuesday, 21 June 2022

Start	End	Program	Chair & Speaker	Institution
9:00 AM	9:05 AM	Opening Remarks on Day 2	Elena Sperk	University Medical Center Mannheim, Germany
9:00 AM	9:05 AM	Opening Remarks on Day 2	Frank A. Giordano	University Hospital Bonn, Germany
9:05 AM	9:45 AM	Keynotes: IORT for Breast Cancer	Frederik Wenz	University Medical Center Freiburg, Germany
9:05 AM	9:45 AM	Keynotes: IORT for Breast Cancer	Bahman Emami	Loyola University Medical Center, USA
		TARGIT IORT during lumpectomy for breast cancer: long-term detailed results from the TARGIT-A trial and update about TARGIT-B trial	Jayant S. Vaidya	University College London, United Kingdom
		Insights into TARGIT-C, -E and -BQR	Elena Sperk	University Medical Center Mannheim, Germany
9:45 AM	10:15 AM	Coffee Break
10:15 AM	11:20 AM	Session: Brain and Spine II	Gustavo R. Sarria	University Hospital Bonn, Germany
10:15 AM	11:20 AM	Session: Brain and Spine II	Douglas Guedes	Hospital Alemão Oswaldo Cruz, Brazil
		Keynote: Technical considerations for BrainMet IORT: Surgeon's perspective	Bernhard Meyer	Technical University Munich, Germany
		Keynote: Special cases in IORT for brain metastases	Ehab Shiban	University Hospital Augsburg, Germany
		Keynote: Kypho-IORT as a treatment option for spinal metastases	Frederic Bludau	University Medical Center Mannheim, Germany
		Two unusual intraoperative radiation therapy cases: treatment of brain metastasis for pregnant patient and simultaneous treatment of two brain metastases	Kynann Putra Aninditha	Klinikum Stuttgart, Germany
		Dosimetric comparison of upfront boosting with stereotactic radiosurgery versus intraoperative radiotherapy for glioblastoma	Gustavo R. Sarria	University Hospital Bonn, Germany
11:20 AM	12:05 PM	Keynotes: Clinical Trials on IORT for Brain Metastases	Stephanie Combs	Technical University Munich, Germany
11:20 AM	12:05 PM	Keynotes: Clinical Trials on IORT for Brain Metastases	Kevin Petrecca	McGill University Health Centre, Canada
		Prospective clinical trial on IORT for brain metastases in Brazil	Douglas Guedes	Hospital Alemao Oswaldo Cruz, Brazil
		IORT after surgical resection of brain metastases: a phase II clinical study	Miquel Macia	Institut Catala d'Oncologia, Spain
		INTRAMET	Stefanie Brehmer	University Medical Center Mannheim, Germany
12:05 PM	1:30 PM	Lunch Break
1:30 PM	2:40 PM	Session: Gastrointestinal, Head & Neck, Sarcoma	Christopher Schmeel	University Hospital Bonn, Germany
1:30 PM	2:40 PM	Session: Gastrointestinal, Head & Neck, Sarcoma	Davide Scafa	University Hospital Bonn, Germany
		Keynote: IORT for head & neck tumors	Bahman Emami	Loyola University Medical Center, USA
		Keynote: Immune response & phase II clinical trial for pancreas cancer	Joon Seong Park	Gangnam Severance Hospital, South Korea
		IORT in pelvic disease: the experience of the European Institute of Oncology	Roberta Lazzari	European Institute of Oncology, Italy
		IORT for pancreatic tumors: rationale and first clinical experiences	Gustavo J. Sarria	AUNA Oncosalud Clinic, Peru
		Intraoperative radiotherapy with photons for pelvic tumors	Amalia Palacios-Eito	Reina Sofia University Hospital, Spain
		Intraoperative radiotherapy safety and efficacy in treatment of locally advanced laryngeal cancer	Yining Yang	Tianjin First Central Hospital, China
2:40 PM	3:10 PM	Coffee Break
3:10 PM	3:55 PM	Session: Physics & Biology	Frank Schneider	University Medical Center Mannheim, Germany
3:10 PM	3:55 PM	Session: Physics & Biology	Stephan Garbe	University Hospital Bonn, Germany
		Keynote: Treatment planning in IORT	Frank Schneider	University Medical Center Mannheim, Germany
		X-ray source navigation using optical tracking - a feasibility study	Sarah Fremgen	University Medical Center Mannheim, Germany
		Effect of dosimetry formalism on dose to organs at risk in intraoperative radiotherapy of glioblastoma	Peter Watson	McGill University Health Centre, Canada
		Dosimetric comparison of intraoperative radiotherapy and SRS for liver metastases	Davide Scafa	University Hospital Bonn, Germany
3:55 PM	4:00 PM	Closing Remarks & Goodbye	Elena Sperk	University Medical Center Mannheim, Germany
3:55 PM	4:00 PM	Closing Remarks & Goodbye	Frank Giordano	University Hospital Bonn, Germany

Following the main program, we would like to invite you to an evening reception at the Kameha Grand Bonn with further scientific program. Be excited – another highlight awaits you.

Abstract Submission

Abstract submission for ILEXIUM will take place via a dedicated abstract submission portal for which you will get the respective link after your successful event registration.

Register yourself via the form below.
Receive a confirmation email after successful registration.
Click on the link in the confirmation email.
Submit your abstract in the abstract submission portal.

The deadline to submit your abstract has been extended again – latest deadline is 06 June 2022. Afterwards the abstract submission for ILEXIUM is closed.

All submitted abstracts will be reviewed and evaluated by the scientific committee for oral presentations or poster sessions. You will receive the corresponding notification via email directly from the scientific committee by end of May 2022.

Abstract guidelines

An abstract is an outline/brief summary of your paper and your whole project. Abstracts must include sufficient information for reviewers to judge the nature and significance of the topic, the adequacy of the investigative strategy, the nature of the results, and the conclusions.

Basis format for abstract:

Abstract titles should be short (length no more than 12 words), but descriptive. informative titles, indicating key points are encouraged. Abbreviations should not be used in the title.
Keywords should be provided (between 5-10 words), written in lowercase letters (not applicable to names/scientific names) and should be separated with commas.
It should be one column of text with a limit of maximum 350 words (minimum 250 words). Acronyms should be written in full the first time, mentioned in the text, followed by the abbreviation in parentheses.
Please do not include subheadings, bullets, lists and header/footer in the abstract.
Always follow SI units.
Scientific names must be in Italic.
There shall be no citations or references in the abstract specifically. If there is a need to cite references, please provide the sources in brackets.

Font:
Title: Times New Roman, 12 points, Upper case, centered text in bold
Body: Times New Roman, 11 points, Line spacing: 1, one column of text

Authors:
Please double check that the names of author(s) and their affiliation(s) are correctly spelled and formatted, with appropriate capitalization and punctuation. Names and affiliations cannot be edited by the submitter once submitted, and will be published exactly as indicated.

Affiliations:
Affiliations should be indicated with superscript Arabic numbers appearing at the end of surname/family name.

Abstract Evaluation Criteria

During the abstract selection process, the following 12 points are used as a guide for evaluation criteria. We strongly recommend that you ensure your abstract satisfies these points.

Does the abstract title describe the subject being written about?
Does the abstract capture the interest of a potential reader of the paper?
Is the abstract well written in terms of language, grammar, etc.?
Does the abstract engage the reader by telling her/him what the paper is about and why they should read it?
Does the abstract make a clear statement of the topic of the paper and the research question?
Does the abstract say how the research was/is being undertaken?
Does the abstract indicate the value of the findings and to whom they will be of use?
Does the abstract describe the work to be discussed in the paper?
Does the abstract give a concise summary of the findings?
Does the abstract conform to the word limit of 350 words?
Does the abstract have between 5 and 10 keywords or phrases that closely reflect the content of the paper?
Should the abstract be accepted?

Your stay in Bonn

Fascinating & Impressive

Bonn, known as the former capital of the Federal Republic of Germany, is located in the beautiful Central Rhine Valley and fascinates with its impressive building monuments and landmarks. It is the birthplace of Ludwig van Beethoven who is one of the most famous composers of the last centuries. Beside the congress, take your time and enjoy the city of Bonn – it is definitely worth exploring.

How to get to ILEXIUM

ILEXIUM 2022

Kameha Grand Bonn
Am Bonner Bogen 1
53227 Bonn
Germany

Anfahrt

Venue
Kameha Grand Bonn
Am Bonner Bogen 1
53227 Bonn
Germany

There is no specific shuttle service. Please use public transportation or take a cab for your travels.

Hotel reservation

For your stay in Bonn, several hotels are available in the surroundings of the venue. We kindly ask you to personally reserve your accommodations.

A limited hotel room contingent is available at the hotels below until four weeks before the event. If you are interested in one of these hotels, please make your reservation directly at the hotel via email and use the reservation code from your registration confirmation email. Please note that the reservation code is not valid for booking portals.

Maritim Hotel Bonn
Godesberger Allee
53111 Bonn, Germany
Reservierung .bonn @maritim .de
Go to website

Hotel Bonn City
Am Marthashof 1
53111 Bonn, Germany
in fo @hotelbonncity .de
Go to website

IntercityHotel Bonn
Quantiusstraße 22
53111 Bonn, Germany
Reservations .bonn @intercityhotel .com
Go to website

AMERON Bonn Hotel Königshof
Adenauerallee 9
53111 Bonn, Germany
Reserv ierung @hotel -koenigshof -bonn .de
Go to website

Hilton Bonn
Berliner Freiheit 2
53111 Bonn, Germany
Reservations .bonn @hilton .com
Go to website

There will be no coverage for additional associated costs such as hotel, transfer, parking or any additional expenses for family and spouses by the event organizer.

Registration closed!

_{¹ I hereby give Carl Zeiss Meditec AG, Göschwitzer Str. 51-52, 07745 Jena, Germany and related companies in accordance with Sections 15ff. German Stock Corporation Act (AktG), ("ZEISS") my permission to disseminate and publish the image(s)/films in which I appear (my "LIKENESS") in course of my participation of ILEXIUM which takes place on June, 20 & 21, 2022 in Bonn, Germany, including for purposes of corporate advertising and the promotion of goods or services. My permission shall apply to all media (e.g. ZEISS homepage, Intranet and social media pages, printed materials such as product brochures etc.) with the exception of television and cinema. It shall also include digitization and editing (e.g. montage or retouching) of the LIKENESS, provided my legitimate interests are not violated. ZEISS shall be entitled to sublicense the contractual rights of use pertaining to the LIKENESS to operators of internet platforms as social media platforms, to use the LIKENESS there as per the particular terms and conditions of the operators. This grant of rights is valid for 2 years from the date of the signing and expires thereafter. This consent is given free of charge.}

_{To all participants for whom “Sunshine” applies: in accordance with the Open Payments (“Sunshine”) provision of the Patient Protection and Affordable Care Act (and similar state laws), the value of food and beverage is subject to public disclosure, and therefore will be reported in compliance with all applicable laws. State of Vermont HCPS: This event was sponsored by Carl Zeiss Meditec AG. Partaking of the food and beverages is prohibited under Vermont’s Gift Ban.}

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ILEXIUM 2022